I have a similar problem. I've been using the mappoint control for 3 months now and the other day it just started coming back with this error.

The only difference i can see is that i am getting this error inside VS and can no longer compile my code.

'AxMapPoint.AxMapPointControl' is not defined

the refereneces are still there, but say:
<the system cannot find the reference specified>

Running XP SP2 and MP2004

any ideas?

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- AlexC